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Double-blind random samples with meaningful doses of psychedelics without selection bias is probably going to be unethical forever. Glad I'm not on that IRB (or any, because I imagine they're tedious places).Volunteer bias, I think - people who volunteer for experiments, surveys, etc are going to be different than those who do not. I chime in with a haven’t you people ever heard of closing the God dang it Bobby shirtJust an example, it means they have an interest in the topic or might even believe in the treatment (which may change the results)This is a study focusing on anecdotal evidence. Very susceptible to selection bias and further more will definitely lead to over estimation of the treatment effect.
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With restricted drugs like this, usually that is the best you can do. You then use that evidence to try and get a formal study done. I chime in with a haven’t you people ever heard of closing the God dang it Bobby shirt MAPS(Multidisciplinary Association of Psychedelic Studies) does a lot of work in this area. They did a lot of pilot studies before they were able to do the more formal studies they are currently doing.
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